Anticholinergic responsive cyclic myoclonus
نویسندگان
چکیده
منابع مشابه
Anticholinergic drugs: response of parkinsonism not responsive to levodopa.
A 41 year old man with parkinsonism and pyramidal signs is described. He was non-responsive to levodopa and dopamine receptor agonists but dramatically responded to trihexyphenidyl. In this patient, brain MRI showed bilateral hyperintensities along the corticospinal tracts on T2 weighted images. PET studies showed a decrease in (18)F-6-fluorodopa uptake in the putamen contralateral to the more ...
متن کاملA Patient with Genetically Confirmed Myoclonus-Dystonia Responded to Anticholinergic Treatment and Improved Spontaneously
BACKGROUND The various medical treatments applied to myoclonus-dystonia patients with a mutation of the ε-sarcoglycan gene (SGCE) have not been beneficial in most cases. Most patients experience progressive deterioration or static clinical courses, with only rare cases of spontaneous remission. CASE REPORT A 19-year-old girl presented with a 14-year history of myoclonus and dystonia that seve...
متن کاملGTP cyclohydrolase I mutations in patients with dystonia responsive to anticholinergic drugs.
OBJECTIVES To investigate the hypothesis that GTP cyclohydrolase I (GCH1) mutations are responsible for the phenotype of highly anticholinergic responsive dystonia in patients with apparent primary torsion dystonia. METHODS From 107 British patients with clinically diagnosed primary torsion dystonia, seven patients were identified with an excellent response to anticholinergic drugs. All six e...
متن کاملCorticosteroid-responsive postmalaria encephalopathy characterized by motor aphasia, myoclonus, and postural tremor.
OBJECTIVES To study the clinical spectrum of an acute severe encephalopathy occurring in 2 patients after recovery from falciparum malaria infection and to compare it with the reported clinical features of the postmalaria neurological syndrome. DESIGN Case report. SETTING Tertiary care hospital. PATIENTS Two patients presented with acute onset of fluctuating motor aphasia, severe generali...
متن کاملAlcohol-responsive Action Myoclonus of the Leg in Prostate Cancer: A Novel Paraneoplastic Syndrome?
BACKGROUND Paraneoplastic movement disorders in prostate cancer are rare, and to our knowledge paraneoplastic myoclonus has not previously been reported. CASE REPORT We report two men with adenocarcinoma of the prostate who developed isolated alcohol-responsive action myoclonus of one leg. Myoclonus was absent at rest but triggered by movement, standing, or walking. Evaluations excluded malig...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Movement Disorders
سال: 2013
ISSN: 0885-3185
DOI: 10.1002/mds.25284